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I am a PhD candidate in the Department of Biostatistics at the University of Michigan. I have been working with Prof. Xiang Zhou on developing statistical methods for genetic and genomic datasets. My recent focus is on developing methods for analyzing spatial transcriptomics. I also work closely with Prof. Jennifer Smith in the Department of Epidemiology at the University of Michigan on large-scale quantitative trait mapping in African Americans in the GENOA study.

Research Interests:

My research interest is in developing effective and efficient statistical and computational methods in single cell and spatial transcriptomics to address critical biological problems such as omics data dimension reduction and integration in genetics and genomics. Specifically, my work consists of three important directions: (1) developing efficient and powerful computational and statistical methods in single cell and spatial transcriptomics; (2) integrating genome-wide association studies (GWASs) with single cell and bulk RNA-seq to understand disease etiology; and (3) performing large-scale quantitative trait association studies in underrepresented populations.

Keywords:

• Statistical Methods: High-dimensional data analysis, mixed effects models, longitudinal data analysis, spatial statistics, non-parametric models, dimension reduction, data integration, statistical computing, network analysis and machine learning.
• Applications: High dimensional genetic and genomic data including spatial transcriptomics, single cell RNA sequencing studies, spatial and single cell multi-omics, genome-wide association studies, genome-wide quantitative loci mapping, methylation studies, and gene regulatory network.